Introduction: One of the main complications of spine tuberculosis is the instability produced by the injury of the articular structures between the vertebrae as well as the adjacent tissues, which, depending on the degree of involvement, can lead to angular kyphosis with the consequent risk of neurological impairment that can end with paraplegia. While the criteria for vertebral instability secondary to tuberculosis were identified and the pathophysiological processes that determine the progression of kyphosis following tuberculosis were determined, there is no new criteria, following Rajasekaran’s 2001 work, which demonstrated which imaging signs could predict a kyphosis progression in children. Study design: Systematic Review. Objective: To determine the most important radiological signs that predict the progression of post-tubercular kyphosis in children. Methods: Systematic review according to the PRISMA criteria on the most important radiological signs that predict the progression of post-vertebral tuberculosis kyphosis in children from January 2017 to July 2022. The keywords used for the search in the MEDLINE/PubMed and Scielo database were: ”(tuberculosis, spinal) and child” and their different combinations with ”(tuberculosis, spinal) and children and kyphosis” and ”(tuberculosis, spinal) and pediatric and kyphosis. Results: Five articles were selected for final evaluation, of which 2 were included, which are those that fit the search criteria. Radiological signs indicating instability were dislocation of facets, posterior retropulsion of diseased fragments, lateral translation of vertebrae in anteroposterior view and collapse of the upper vertebra. Multiple regression analysis showed that a spinal instability score of more than 2 was a reliable predictor that patients would have an increase of more than 30° in deformity and with a final deformity of more than 60°. Conclusion: Although the criteria of vertebral instability secondary to tuberculosis were identified and the pathophysiological processes that determine the progression of kyphosis after this infection were determined, no new criteria were found, after the 2001 work of Rajasekaran, a SORT 2 recommendation level was assigned.